Penile cancer is a rare malignancy that develops in the tissues of the penis. It typically originates in the skin cells or cells of the glands beneath the foreskin. Penile cancer often presents as a growth or sore on the penis, accompanied by symptoms such as changes in skin color, thickening of the skin, persistent discharge, or bleeding. Risk factors include poor hygiene, human papillomavirus (HPV) infection, smoking, and chronic inflammation. Diagnosis involves a physical examination, biopsy, and imaging studies to determine the extent of the cancer. Treatment options vary based on the stage and location of the tumor but may include surgery, radiation therapy, chemotherapy, or targeted therapy. Early detection and prompt treatment are crucial for successful outcomes in penile cancer. Regular self-examinations and medical check-ups can aid in early detection and management.